Rheumatoid Arthritis

Case Studies supporting PEMF benefits for Rheumatoid Arthritis

Analgesic-antiinflammatory effect of a 100 Hz variable magnetic field in RA

For more than 20 years electromagnetic fields (PEMF) have been employed in medical practice, essentially for analgesic purposes. There are numerous studies which report that PEMF are capable of eliciting in vitro and in vivo bioeffects, but a well-accepted biophysical mechanism which quantitatively describes the PEMF coupling to biological systems still remains elusive (1). The aim of this study was to examine some of the physiological effects of a weak magnetic field modulated by a low frequency sinsoidal law, employed for analgesic purposes. We selected 10 patients (5 males and 5 females, mean age 40 ± 3.8 years) affected by rheumatoid arthritis (RA), diagnosed according to the ARA criteria (2) and in a relapsing phase of the disease. These patients (group A) were compared with 10 normal subjects (group B) (5 males and 5 females, mean age 39 ± 4 years).

Effect of Pulsed Magnetic Field on Bone Density in Juvenile Rheumatoid Arthritis

Abstract

Introduction: Juvenile rheumatoid arthritis (JRA) has long been suspected to affect bone mineralization because of poor linear and skeletal growth, an increased number of fractures, and osteopenia, observed by radiography, in children with the disease.

Methods: 30 children, with polyarticular JRA, aged 8 to 12 years were included. Children were randomized for treatment in two groups. In the study group they received pulsed magnetic field therapy 3 times per week for successive 3 months. In the control group they received the conventional physical therapy program only. Evaluation of bone mineral density (BMD) using Dual Energy X-ray Absorptiometry (DEXA) was performed before and after the treatment.

Results: BMD of femur post treatment for the control and study groups was 0.735±0.166 and 0.866±0.125 (g/cm²) respectively. BMD of the lumbar spine for the control and study groups were 0.657±0.121 and 0.75±0.102 (g/cm²) respectively. BMD of total body for the control and study groups were 0.723±0.097 and 0.807±0.11 (g/cm²) respectively. The differences between both groups in their post treatment mean values of BMD was statistically significant as (p<0.05).

Conclusions: Pulsed electromagnetic field therapy is effective, innovative, non-invasive, non-expensive and can be used as a new trend physical therapy modality in the treatment of osteoporosis in JRA.

Effect of Pulsed Magnetic Field on Lean Muscle Mass and Fat Mass In Juvenile Rheumatoid Arthritis

Abstract

Background: The severity of joint pain and joint stiffness and their effects on walking variables especially in children who have juvenile rheumatoid arthritis (JRA) are serious and represent functional problems. So, the aim of this study was to investigate the effect of pulsed magnetic field (PMF) on lean muscle mass and fat mass in children with juvenile rheumatoid arthritis.

Methods: Thirty children with polyarticular JRA were included in this study. Fifteen children represent control group who were treated with therapeutic exercises only and fifteen children represent study group who were treated with pulsed magnetic field and therapeutic exercises. Lean muscle mass and fat mass were determined before and after six months of treatment.

Results: The current Study showed significant changes in both lean muscle mass and fat mass in study group compared with control group. Pre-treatment results of mean lean muscle mass was 23975.2± 8152.21 g. in control group and 24016.26 ± 7864.39 g. in study group. There was no significant difference between both groups which indicate that they were homogenous (p = 0.98). But post-treatment results showed that mean lean muscle mass was 27143.26 ± 8223.52 g. in control group while that of study group was 35755.46 ± 7106.45 g. which was significantly higher than the control group (p = 0.05). Also, pre-treatment results of mean fat mass were 10742.13 ± 5466 g. in control group and 12358.53 ± 6210.27 g. in study group. There was no significant difference between both groups which indicate that they were homogenous (p = 0.45). But post-treatment results showed that mean fat mass was 10008.26 ± 5110.66 g. in control group while that of study group was 6265 ± 3957.92 g. which was statistically significant than the control group (p = 0.03).

Conclusion: Pulsed magnetic field together with therapeutic exercises are effective in increasing lean muscle mass and decreasing fat mass in children with polyarticular JRA than therapeutic exercises alone.

Exposure to a Specific Pulsed Low-Frequency Magnetic Field: A Double-Blind Placebo-Controlled Study of Effects on Pain Ratings in Rheumatoid Arthritis and Fibromyalgia Patients

Abstract

BACKGROUND: Specific pulsed electromagnetic fields (PEMFs) have been shown to induce analgesia (antinociception) in snails, rodents and healthy human volunteers.

OBJECTIVE: The effect of specific PEMF exposure on pain and anxiety ratings was investigated in two patient populations.

DESIGN: A double-blind, randomized, placebo-controlled parallel design was used.

METHOD: The present study investigated the effects of an acute 30 min magnetic field exposure (less than or equal to 400 μTpk; less than 3 kHz) on pain (McGill Pain Questionnaire [MPQ], visual analogue scale [VAS]) and anxiety (VAS) ratings in female rheumatoid arthritis (RA) (n=13; mean age 52 years) and fibromyalgia (FM) patients (n=18; mean age 51 years) who received either the PEMF or sham exposure treatment.

RESULTS: A repeated measures analysis revealed a significant prepost- testing by condition interaction for the MPQ Pain Rating Index total for the RA patients, F(1,11)=5.09, P<0.05, estimate of effect size = 0.32, power = 0.54. A significant pre-post-effect for the same variable was present for the FM patients, F(1,15)=16.2, P<0.01, estimate of effect size = 0.52, power =0.96. Similar findings were found for MPQ subcomponents and the VAS (pain). There was no significant reduction in VAS anxiety ratings pre- to post-exposure for either the RA or FM patients.

CONCLUSION: These findings provide some initial support for the use of PEMF exposure in reducing pain in chronic pain populations and warrants continued investigation into the use of PEMF exposure for short-term pain relief.

Case Study Reference Source:

  • 1. Analgesic-antiinflammatory effect of a 100 Hz variable magnetic field in RA
    (Authors: ARNETT FC, EDWORTHY SM, BLOCH DA)

  • 2. Effect of Pulsed Magnetic Field on Bone Density in Juvenile Rheumatoid Arthritis
    (Authors: Shamekh Mohamed El-Shamy, Hesham Galal Mahran)

  • 3. Effect of Pulsed Magnetic Field on Lean Muscle Mass and Fat Mass In Juvenile Rheumatoid Arthritis
    (Authors: Mohamed A. Eid)

  • 4. Exposure to a Specific Pulsed Low-Frequency Magnetic Field: A Double-Blind Placebo-Controlled Study of Effects on Pain Ratings in Rheumatoid Arthritis and Fibromyalgia Patients
    (Authors: Naomi M Shupak MSc1, Julia C McKay BSc1, Warren R Nielson PhD, Gary B Rollman PhD, Frank S Prato PhD, Alex W Thomas PhD)